Cementoosseous dysplasia may occur in the toothbearing jaw after dental extraction, and when multiple lesions are present, adjacent periapical lesions may coalesce. Management and treatment outcomes of maxillofacial fibro. Fibro osseous lesions classifications, pathophysiology. Pcod or fcod are two different terms for the same reactive lesion. While fd has a typical clinical and histological presentation, considerable variation exists. The term benign fibroosseous lesion is well known and widely used. Sporadic multiple ofs must be distinguished from hyperparathyroidismjaw tumour syndrome hptjt related of and other fibroosseous lesions. Mar 15, 20 fibrous dysplasia and ossifying fibroma of the jaws are fibro osseous lesions with different clinical course and treatment strategies. Victor boyko presented a case of osteofibroma of the mandible associated with leontiasis ossea of the. This is a temporary file and hence do not link it from a website, instead link the url of this page if you wish to link the pdf. Benign fibroosseous lesions bfol of the jaw, facial and skull bones are a variant group of intraosseous disease processes that share microscopic features 14. The florid variant may involve the entire mandible.
In the second patient, trache otomy was avoided by the use of an intubating bronchoscope. Fibro osseous lesions of jaws were more in females 61. The diagnosis based on microscopy alone is often impossible due to overlapping of histopathologic features. The clinical, radiographic, and pathologic features of five cases are presented, and this uncommon. Fibroosseous lesions of the face and skull with aneurysmal. Clinical study of benign and malignant fibrousosseous. Aneurysmal bone cyst engraftment on benign fibroosseous lesions, well known to occur in the extracranial skeleton, has been reported infrequently in the craniofacial bones. Growth of lesion usually ceases at the end of skeletal growth.
Fibroosseous lesions of the craniofacial bones cambridge core. Clinical study of benign and malignant fibrousosseous lesions of the jaws 33 of follow up, 5 of 8 cases survived. Fibro osseous lesions of the jaws usually present a diagnostic dilemma for the clinician as well as the pathologist. Maxillofacial fibroosseous lesions fol consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the rest of the skeleton. Benign fibroosseous lesions is a group of lesions in which normal bone is replaced initially by fibrous connective tissue and over a period of time, the lesion is infiltrated by osteoid and cementoid tissue. Benign fibro osseous lesions bfols represent a group of conditions that share the same basic evolutive mechanism and are characterized by the replacement of normal bone with a fibrous connective tissue that gradually undergoes mineralization. It encompasses a broad range of conditions, the diagnosis of which can be both challenging and confusing. All are characterized by the replacement of bone by cellular fibrous tissue containing foci of mineralization that vary in amount and appearance. When this combined lesion occurs in the skull the clinical and radiographic features often suggest an aggressive neoplasm.
In this study, we examined the epidemiological, clinical, and path. Fibro osseous lesions are characterized by the presence of bone marrow that has changed into fibrous tissue and that contains mineralized material of varying appearances. Cementoosseous dysplasia lesions may be expansile when associated with bone cysts or osteomyelitis. Fibro osseous lesions classifications, pathophysiology and.
Hence, this study was designed to provide a demographic data on the odontogenic tumors and giant cell lesions reported from. Jonathan swift 1667 1745 benign fibroosseous lesions a group of lesions in which normal bone is replaced initially by fibrous connective tissue over time, the lesion is infiltrated by osteoid. This pattern consists of a bland spindle cell population mixed with varying amounts of woven bone and occurs in fibrous dysplasia, ossifying fibroma, and osseous dysplasia. Fibro osseous lesions of the jaws comprise a diverse group of conditions, which are characterized by replacement of normal bone by fibroblasts, collagen fibers, and mineralized tissue. Diagnosing the most common odontogenic cystic and osseous.
In the revised second edition of who, fibroosseous lesion was classified in neoplasms and other lesions of the bone except benign. Continuous observations on osteosarcoma and ewings sarcoma are very important and should be checked every two months after surgery. The clinical, radiographic, and pathologic features of five cases are. Recent world health organization classification 2005 for fibroosseous lesions was considered while sub. In the first patient, blind nasal intubation was successful. A clinicopathologic analysis of 207 cases of benign fibro. All fibro osseous lesions of the jaw and face are variations of the same histologic pattern. Cementoosseous dysplasia is a benign fibroosseous lesion of the toothbearing region of the jaws with a periodontal ligament origin.
Benign fibroosseous lesions of the craniofacial skeleton bfol are a variant group of intraosseous disease processes that share similar microscopic features characterized by hypercellular fibroblastic stroma containing various combinations of bone or cementumlike tissue and other calcified structures 16. Fibroosseous, lesion jaw definition of fibroosseous. Some may be part of more generalized systemic disease. Autosomal dominant mesomandibular fibroosseous dysplasia. Aneurysmal bone cyst engraftment on benign fibro osseous lesions, well known to occur in the extracranial skeleton, has been reported infrequently in the craniofacial bones. Ossifying fibromas are typically encapsulated, circumscribed, benign neoplasms made up of highly cellular fibrous connective tissue that contains varying. Pdf fibroosseous lesions of the maxillofacial bones comprise a diverse group of pathologic conditions that include developmental. May, 2008 periapical cementoosseous dysplasia pcod and focal cementoosseous dysplasia fcod represent the most common fibroosseous lesions of the jaws 6, 99102. It cannot be over emphasized that in the case of fibro osseous lesions of the jaws, the radiograph can be the diagnostic discriminator as the histopathology of a number of lesions can appear very. Fibroosseous lesions of jaw are a diverse group and since it may not be possible to adequately separate them.
Fibroosseous lesions of the face and jaws request pdf. A nosologic problem in the diagnosis of fibroosseous lesions of the jaws. Benign fibroosseous lesions occur commonly in the jaw. Department of pathology, radboud university, nijmegen medical centre, the netherlands. Gnas mutational analysis in differentiating fibrous dysplasia. Fibro osseous lesions fols are a generic designation of poorly defined group of lesions which are. This matrix displays varying degrees of mineralization in the form of woven bone or of cementumlike round acellular intensely basophilic structures. This is a temporary file and hence do not link it from a website, instead link the url of this page if you wish to link the pdf file. Fibroosseous lesions and benign tumors of the jaw bone. Typically, the lesion is asymptomatic and is detected on routine radiographic examination. It will become apparent that for this group of conditions, diagnosis. Fibroosseous lesions of jaws were more in females 61.
Oct 28, 2016 odontogenic neoplasms that fit into the category of benign fibroosseous lesions include the ossifying fibroma and the benign cementoblastoma. Fibroosseous lesions of the jaws usually present a diagnostic dilemma for the clinician as well as the pathologist. Fibroosseous lesions in adults have been well documented in many studies and although they often occur in children and adolescents, relevant reports are rather infrequent. Benign fibroosseous lesion bfol is a distinct group of jaw entities composed of fibrocellular tissue and mineralized materials. Fibro osseous lesions of jaws dental implant courses by. Request pdf fibroosseous lesions of the face and jaws maxillofacial fibroosseous lesions fol consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the. Fibro osseous lesions 1 fibro osseous lesions dr shabeel pn 2 introduction. More recently, eversole 2008 classified the benign fol based on the pathogenetic mechanisms and the lesions included neoplasms, developmental lesions and inflammatory or reactive processes. Odontogenic tumors and giant cell lesions of jaws a nine. Benign fibro osseous lesion bfol is a distinct group of jaw entities composed of fibrocellular tissue and mineralized materials. Fibroosseous lesions and benign tumors of the jaw free download as powerpoint presentation. Fibroosseous lesions of the face and jaws sciencedirect. This chapter demonstrates the variation in the radiological appearances of conditions of fibro. Original article spectrum of fibro osseous lesions.
Other lesions, not strictly odontogenic but also mainly confined to the jaw bones, are giant cell lesions, fibro. Fibroosseous lesions of the head and neck diagnostic. Bone in fd showing mixed radiolucentradiopaque may be vulnerable to infection. Benign fibro osseous lesions occur commonly in the jaw. A definite geographic variation has been observed in the frequency of odontogenic tumors and giant cell lesions of the jaws reported from different parts of the world. Its importance is that it could mimic a periapical lesion in the early, translucent stage. They represent a group of diverse diseases characterized by similar histopathologic features, 6. Journa of enta an ra eath 9 s e e pwt scientonlineorg ent oral ealth issn 23 research article scient open access exploring the world of science pattern of fibro osseous lesions of the jaws in kano, northern nigeria sule aa 1, iyogun ca2 and adeyemi te3 1department of pathology, bayero university kano aminu kano teaching hospital, kano. Whereas some are diagnosable histologically, most require a combined assessment of clinical, microscopic and radiologic features. Fibroosseous lesions fol are a poorly defined group of lesions affecting the jaws and craniofacial bones. Florid cementoosseous dysplasia fcod is a condition that occurs in the jaw bone, especially close to where the teeth are formed.
Fibroosseous lesions of the jaws linkedin slideshare. Two brothers with hippopotamus face deformities presented for corrective surgery under general anaesthesia. D dept of oral and maxillofacial surgery,vspms dental college, nagpur 2. In the first volume of the journal of oral surgery, dr g. Jonathan swift 1667 1745 benign fibroosseous lesions. Odontogenic neoplasms that fit into the category of benign fibroosseous lesions include the ossifying fibroma and the benign cementoblastoma. However, there are a few studies on these lesions, especially giant cell lesions, reported from india. It appears predominantly in black and asian middleaged females.
Radiologically, this lesion has three stages of maturation. The size and extent of the lesions are the major determinants of their degrees of morbidity. Gnas mutational analysis in differentiating fibrous. Request pdf fibroosseous lesions of the face and jaws maxillofacial fibro osseous lesions fol consists of lesions that differ, with the exception of fibrous dysplasia, to those found in the. Moreover, overlap of features with other disorders is possible. Hence, this study was designed to provide a demographic data on the odontogenic tumors and giant. Fibroosseous lesions fol represent a varied group of entities in which the normal bone is replaced by cellular fibrous tissue containing mineralized foci that may vary in amount and appearance. It cannot be over emphasized that in the case of fibroosseous lesions of the jaws, the radiograph can be the diagnostic discriminator as the histopathology of a number of lesions can appear very. Fibroosseous lesions are disturbances in bone metabolism in which normal bone is replaced by a connective tissue matrix that then gradually develops into cementoosseous tissue. The purpose of this retrospective study was to evaluate the characteristics, treatment outcome of benign fibroosseous lesions of the jaws, in children, adolescents and adults.
In this report a rare case of familial cementoosseous dysplasia is. People with fcod develop lesions in the jaw, were spots of normal bone are replaced with a mix of connective tissue and abnormal bone. Multiple of cases were identified from ossifying fibroma cases. Nov 30, 2014 fibroosseous lesions the term fibroosseous lesion fol is a generic designation of a group of jaw disorders characterized by the replacement of bone by a benign connective tissue matrix. Focal cementoosseous dysplasia of mandible bmj case reports. Fibro osseous lesions of jaw are a diverse group and since it may not be possible to adequately separate them. Benign fibroosseous lesions of the craniofacial complex a.
Report of three casesturkiye klinikleri j dental sci 2007. This group includes fibrous dysplasia, ossifying fibroma, focal cemento osseous. Introduction fibroosseous lesions comprise a diverse group of pathologic conditions that includes developmental lesions, reactive or dysplastic diseases, and neoplasms. Benign fibroosseous lesions bfols represent a group of conditions that share the same basic evolutive. A hereditary congenital condition characterized by a fibroosseous lesion sharing some features with fibrous dysplasia and affecting the middle aspect of the mandible is presented. Fibrous dysplasia and ossifying fibroma of the jaws are fibroosseous lesions with different clinical course and treatment strategies. These group of lesions predominantly affects the jaws and craniofacial bones. Fibroosseous lesions 1 fibroosseous lesions dr shabeel pn 2 introduction.
Journa of enta an ra eath 9 s e e pwt scientonlineorg ent oral ealth issn 23 research article scient open access exploring the world of science pattern of fibroosseous lesions of the jaws in kano, northern nigeria sule aa 1, iyogun ca2 and adeyemi te3 1department of pathology, bayero university kano aminu kano teaching hospital, kano. Its differential diagnosis should take into account the stage of development of the lesion and the possibility of. Depending on the proportions of soft and mineralized tissue, they may be predominantly radiolucent, mixed radiodenseradiolucent, or mainly radiodense. Benign fibro osseous condition involving one or more bones of the cranial and extracranial skeleton, consists of nonencapsulated lesions which show replacement of normal bone by cellular fibrous tissues edwards 1984 originally introduced by lichtenstein in 1938 one of the most perplexing diseases of osseous tissues. This group includes fibrous dysplasia, ossifying fibroma, focal cementoosseous. Radiographic patterns of fibroosseous lesions in the jaws.
The term fol is a generic designation of a group of bone disorders characterized by the replacement of bone by a benign connective tissue matrix that displays varying degrees of mineralization in the form of woven bone or cementum. The lesions are often found in equal numbers and size on both sides of the jaw. Monostotic and polyostitic fibrous dysplasias affect larger areas in the craniofacial complex. Fibroosseous lesions of the jaws in ibadan, nigeria. Two cases of multiple ossifying fibromas in the jaws. Difficulties in the diagnosis of periapical translucencies. Under this classification, the major fibroosseous lesions include fibrous dysplasia fd, osseous dysplasia, ossifying fibroma with their various subtypes.
Benign fibroosseous lesions bfols represent a group of conditions that share the same basic evolutive mechanism and are characterized by the replacement of normal bone with a fibrous connective tissue that gradually undergoes mineralization. Fibro osseous lesions fol are a poorly defined group of lesions affecting the jaws and craniofacial bones. The clinicopathologic characteristics of multiple ossifying fibroma of are unclear due to the conditions rarity, making diagnosis challenging. This study serves to characterize the features of a large case series of fd of the jaws. Fibroosseous lesions of the jaws comprise a diverse group of conditions, which are characterized by replacement of normal bone by fibroblasts, collagen fibers, and mineralized tissue. However, there is sufficient evidence that the disorder is autosomal. Fols of the face and jaws are cementoossifying dysplasia, fibrous dysplasia and cementoossifying fibroma. Cementoosseous dysplasia is the most common fibroosseous lesion occurring in the tooth bearing areas of the jaws. Fibrous dysplasia fd is a rare condition commonly involving the jaws. Ppt fibroosseous lesions powerpoint presentation free to.
Fibrous dysplasia may present with painless facial swelling and asymmetry. These form a diverse group of conditions with differing aetiologies but similar histological appearances and some may be part of more generalized systemic disease. Fibro osseous lesions fol represent a varied group of entities in which the normal bone is replaced by cellular fibrous tissue containing mineralized foci that may vary in amount and appearance. A case series of fibroosseous lesions of the jaws ncbi.
It will become apparent that for this group of conditions. Fibroosseous lesions of the jaws has been accepted as a general designation for lesions characterized by the cellular or fibrous tissue containing various amounts of bony or cementumlike tissues. Benign fibroosseous lesions of the jaws pocket dentistry. Cod denotes an extensive process with multifocal involvement of the jaws by lesional tissue with the same. Mar 11, 2009 this latter point, especially, results in the presence of lesions that are not found in other bones, a broad variety of odontogenic cysts and tumours.
The mandible was more affected than the maxilla, except in fds. The term benign fibroosseous lesion refers to a group of nonneoplastic conditions in which normal bone is replaced with a fibrous connective tissue matrix containing abnormal bone or cementum. Mar 28, 2014 the clinicopathologic characteristics of multiple ossifying fibroma of are unclear due to the conditions rarity, making diagnosis challenging. A clinicopathologic analysis of 207 cases of benign fibroosseous lesions of the jaws ekarat phattarataratip, dds, phd, chanajit pholjaroen, dds, and prawwalee tiranon, dds international journal of surgical pathology 20 22. Benign fibro osseous lesions is a group of lesions in which normal bone is replaced initially by fibrous connective tissue and over a period of time, the lesion is infiltrated by osteoid and cementoid tissue. Ppt fibroosseous lesions powerpoint presentation free. Fibroosseous lesions are characterized by the presence of bone marrow that has changed into fibrous tissue and that contains mineralized material of varying appearances. The condition was initially described as congenital monostotic fibrous dysplasia in two siblings, a male and a female. Fibroosseous lesions the term fibroosseous lesion fol is a generic designation of a group of jaw disorders characterized by the replacement of bone by a benign connective tissue matrix. Fibroosseous lesions of the oral and maxillofacial. The diagnosis based on microscopy alone is often impossible due. Fibroosseous lesions of the oral and maxillofacial region.
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